3D Tissue Constructs from the Ground Up for Game Changing New Applications in Tissue Engineering and Regenerative Medicine

Pallavi Tripathi¹, Sunny O. Abarikwu²*

¹Intertek Pharmaceutical Services Manchester, Manchester, UK.

²Department of Biochemistry, University of Port Harcourt Choba, Nigeria.

Abstract

In view of the very expensive modern healthcare system, sudden loss or failure of organs and tissues could pose a very difficult and costly medical problem to patients. Further, the limited supply of organs globally that a patient can afford for replacement in the event of an organ failure makes the problem even more challenging and complicated. These medical and healthcare challenges have triggered research and developments into tissue engineering to advance the field of regenerative medicine. Especially, the research focus has been on the design, development and optimization of a cell-scaffold-microenvironment to promote the regeneration of various types of tissue including skin, cartilage, bone, tendon and cardiac tissue, to name a few. Studies have been undertaken to produce functional three-dimensional (3D) tissue substitutes or constructs that are based on bio scaffolds from the ground up. To this end, bioprinting strategies have been considered for fabrication of complex 3D functional living tissues or artificial organs. Here, we describe some notable advances in laser bioprinting enabled tissue engineering, which is a rapidly emerging field in 3D biofabrication technology for applications in regenerative medicine.

Keywords:  3D bioprinting, laser assisted bioprinting, tissue engineering, artificial organs 

*Corresponding author: Sunny O. Abarikwu

E-mail address: sunny.abarikwu@uniport.edu.ng

DOI: https://doi.org/10.37756/bk.22.4.3.2

Article type: Feature

Received: January 5, 2022

Revised: January 29, 2022

Accepted: February 5, 2022

Please cite this article as: Tripathi P and Abarikwu S, 3D Tissue Constructs from the Ground Up for Game Changing New Applications in Tissue Engineering and Regenerative Medicine, Biotechnol. kiosk, Vol 4, Issue 3, PP: 17-31 (2022); DOI: https://doi.org/10.37756/bk.22.4.3.2